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IRMA : Imatinib Resistance Mutation Analysis Test and Its Price in Delhi, India

Imatinib Resistance Mutation Analysis

IRMA: Imatinib Resistance Mutation Analysis

Book IRMA: Imatinib Resistance Mutation Analysis Appointment Online at the best price in Delhi/NCR from Ganesh Diagnostic. NABL & NABH Accredited Diagnostic centre in Delhi offering a wide range of Radiology & Pathology tests. Get Free Ambulance & Free Sample collection from Home. 24 Hour Open.

₹ 10080 ₹ 8064

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This test is used to recognise resistance to Imatinib doses in patients who have chronic myeloid leukemia.

What is Imatinib used for?

This is a tyrosine kinase inhibitor. It is employed in the therapy of leukemias. It is a drug used in the cure of chronic myeloid leukemias.

It is also used in the following cases

  • Treating Gastrointestinal tumours.
  • Treating fibrosarcomas.
  • Immune system disorders
  • Acute lymphocytic leukemia
  • Systemic mastocytosis
  • Eosinophilic leukemia

Side effects

  • Dizziness
  • Blurry vision
  • Cramps
  • Joint pain
  • Headache
  • Nausea
  • Loss of appetite
  • Diarrhea
  • Muscle pain
  • Drowsiness
  • Rashes
  • Hemorrhage
  • Liver disorders

What causes Imatinib Resistance?

It is seen in patients having doses of imatinib during chronic myeloid leukemia. It occurs due to point mutation seen in the ABL-1 kinase of BCR-ABL1. It interferes with the binding of BCR- ABL molecules.

Leukemia:

>>Leukos: "White"
>>Blood: "Haima"

Cause of leukemia

When the blood cells start developing abnormally, it causes leukemia.

Variants of leukemia

It can be acute or chronic

  • Lymphocytic Leukemia
  • myeloid Leukemia

Chronic myeloid leukemia

In this ailment, the number of white blood cells is increased. It is slow in progression, and this type of leukemia is rarely seen.

Symptoms seen are

  • Fatigue
  • Fever
  • Loss of weight
  • Splenomegaly
  • Abdominal pain
  • Bone pain
  • Easy bleeding
  • Fullness below ribs
  • Night sweats
  • Loss of appetite

It is a fatal disorder.

Risk Factors

  • Males
  • Old age
  • Radiation exposure

Phases of Chronic myeloid leukemia

  • Chronic Phase
  • Accelerated Phase
  • Blastic Phase

Mutation

It refers to a non-specific change in the DNA of the chromosome. It can be of the following types:

  • Deletion
  • Insertion
  • Duplication
  • Transportation

Procedure

  • A blood sample is required
  • The needle is pricked into the arm.
  • Blood is withdrawn.

Test Type IRMA: Imatinib Resistance Mutation Analysis
Includes

IRMA : Imatinib Resistance Mutation Analysis Test (Oncology)

Preparation
Reporting

Within 24 hours*

Test Price ₹ 8064 ₹ 10080
Frequently Asked Questions
FAQ

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