P1NP (Procollagen Type 1 Amino Terminal Propeptide), Total Test Cost & Procedure

This test indicates osteoblastic effects and disorders like Paget's disease. This also determines the impact of medications. This test monitors bone formation.

What is Procollagen type 1 N Propeptide (P1NP)?

This is formed during the formation of collagen from procollagen. It is included in the bone. The level of P1NP is increased in bone disorders. It tells the efficacy of bone formation.

Bone:

Bone is a tissue that regrows and breaks continuously. It has various minerals like calcium, phosphorus and iron.

Paget's Disease:

In this disease, there is excessive breakdown of bone. Fractures constantly occur in the bones.

Causes:

It happens due to environmental factors or genetics.

What is Osteocalcin?

It is also known as Bone Gla protein. It is one of the proteins present in the Bone matrix. Osteoblasts are responsible for the generation of osteocalcin. This protein helps the formation of Bone. If its rate is altered, it is used in accessing osteoporosis in women. Osteocalcin is the most critical non-collagen protein in the bone matrix. It is found in abundance in the teeth and bones.

Osteoporosis:

This disorder makes bones brittle and easily breakable. It becomes that brittle, and even on coughing, a fracture occurs. There is no bone formation, and only loss of bone is seen. This disorder of bone lowers the density of bone and mass. Vitamin D. does bone production. If a proper amount of Vitamin D is not there, bone formation is affected. This disorder makes the bone weak and prone to fracture. This disease may not show any symptoms like pain. The bone becomes porous. The strength is highly affected.

Symptoms seen are :

• Low height
• Shortness of breath
• Posture change
• Pain in the lower back
• Weak nails
• Bone fractures
• Receding gums
• Low strength bones

Treatment:

This test is essential for the treatment of osteoporosis. It tells the doctor about the density of bone and mass of bone which helps in deciding the dosage of the medicines to be prescribed. The treatment cannot cure osteoporosis, but it can limit the consequences. Treatment does the following:

• Maintain healthy bone density.
• Reduces fracture
• Limit pain
• Increase the lifespan of the person
• Slow down osteoporosis Person’s ability to continue with their daily life.