Osmotic Fragility Test

Osmotic Fragility Test

Osmotic Fragility Test

What is the Osmotic Fragility Test?

Osmotic Fragility Testing is a simple blood test. During the osmotic fragility test, your red blood cells are introduced to various salt solutions. Spherocytosis or thalassemia frequently implies fragile cells.

An osmotic fragility test can help detect thalassemia and hereditary spherocytosis:

  • Thalassemia produces abnormal haemoglobin production. Haemoglobin is the oxygen-carrying protein in red blood cells. Red blood cells are more likely to be damaged in thalassemia. Anaemia can result.
  • Hereditary spherocytosis affects the outer layer of red blood cells, causing form distortion. This causes fragile red blood cells and premature destruction, causing anaemia.

Why Done? 

Thalassemia is a condition in which your body creates a strange kind of haemoglobin that prevents red blood cells from carrying oxygen. Hereditary spherocytosis is when the outer coating of red blood cells is damaged, resulting in anaemia. Anaemia is characterized by fatigue, shortness of breath, palpitations, dizziness, and the inability to exercise vigorously.


An osmotic fragility test requires a blood sample. You'll have blood extracted from an arm vein, and your red blood cells will be broken down in a salt solution. The test is positive if your red blood cells are more brittle than average.

How does one prepare for the test? 

No preparation is needed.

Required Documents for Osmotic Fragility Test:

  • Doctor prescription. 
  • A valid government ID.

After Care: 

No particular type of care is required.

Cost of Osmotic Fragility Test in Delhi: 

The Osmotic Fragility Test cost varies by region and facility. So constantly get tested at trustworthy diagnostic centres like Ganesh Diagnostic, staffed by trained and experienced professionals to assure patient and visitor safety.



Test Type Osmotic Fragility Test
Test Price: ₹ 350 ₹ 500
100% Safe & Hygienic

100% Safe & Hygienic

Affordable Pricing

Affordable Pricing

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Ambulance Service

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View Report Online

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