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Metanephrine Total Test Cost & Procedure

Metanephrine Total

Metanephrine Total

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When a doctor suspects that a patient has a catecholamine-secreting tumour or wishes to rule it out, they will perform a metanephrines test. When a person (particularly someone under the age of 40) has unexpected spikes in signs and symptoms like:

  • high blood pressure
  • bad headaches
  • Sweating
  • Flushing
  • Quick heartbeat
  • Tremor

Additionally, you could experience anxiety, tremors, a fever, nausea, vomiting, heat intolerance, chest pain, and weight loss.

A healthcare professional may reassess a patient's medications, food, and level of stress if their metanephrine levels are just minimally raised to check for any potential confounding factors. After these issues are remedied, the person may undergo testing once more to see if their levels of metanephrine are still elevated and to choose the best course of action.

To determine whether a

  • catecholamine-secreting tumour is present, the 24-hour urine metanephrines test may occasionally be performed in conjunction with plasma-free metanephrines testing and/or after catecholamines testing.

Preparation for the Metanephrines Test

Avoid strenuous exercise, caffeine-containing drinks, and alcohol consumption before your test. Acetaminophen shouldn't be consumed for at least 48 hours before the test. Make an effort to relax.

Before your blood sample is taken, you might be advised to relax quietly for 15 to 30 minutes.

Metanephrine uses Testing for urine metanephrines can be used to identify or rule out the presence of a paraganglioma, a rare tumour known as a pheochromocytoma, which secretes too much metanephrine.

Testing may also be done to check for recurrence after a tumour has been excised or treated. False positive results might happen with the metanephrine test since it is so sensitive. Stress, narcotics, smoking, and numerous foods, including alcoholic beverages and caffeine-containing beverages, all have an impact on the test.

How to Perform a Metanephrine Test?

  • The metanephrine and normetanephrine levels in your blood are measured by the metanephrine test.
  • It assists in determining whether you have pheochromocytoma, an adrenal gland tumour.
  • A 24-hour urine sample is required for this test.
  •  You must collect all of your urine for 24 hours to provide this sample.
  • First thing in the morning, empty your bladder thoroughly without collecting it.
  • Every time you use the restroom for the following 24 hours, take note of the time and collect your pee.
  •  You'll likely receive precise instructions from your healthcare professional. Observe them closely.

Test Type Metanephrine Total
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Metanephrine Total (Pathology Test)

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Within 24 hours*

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