Lysozyme (Muramidase) Test Cost & Procedure

Lysozyme (Muramidase) - Lysozyme in the serum is mainly due to the deterioration of granulocytes and monocytes and its concentration mirrors the change of these cells. Increases are seen in benign and malignant tumors. Serum lysozyme is raised in individuals with acute or chronic granulocytic or monocytic leukemias and grades drop with flourishing remedy. Conversely, individuals with lymphocytic leukemia may have low plasma lysozyme grades.

Short Description

Lysozyme is a bacteriolytic enzyme that mainly exists in granulocytes, monocytes & histiocytes. The plasma grades contemplate the deterioration of granulocytes and monocytes. Boosted grades are noticed in benign ailments such as diseases and malignant processes such as Leukemias. Lymphocytic leukemias exhibit diminished levels. This examination helps verify a boost in the granulocyte or monocyte in Granulocytic / Monocytic leukemias, Myeloproliferative diseases, and Metastatic histiocytosis.

Test Overview

>> Test Methodology:Turbidimetric

Consideration Value

> or =12 months: 2.6-6.0 mcg/mL. Consideration ranges have not been appointed for individuals who are minor than 12 months of age.

Examination Limitations

Boosted grades may be noticed in nonmalignant diseases comprising sarcoidosis, illnesses, Crohn’s disorder, renal transplant rejection, and additional renal diseases.

Sample Requirements

Compilation Instructions 

Accumulate the sample in the lavender cap tube.

Indication

Serum lysozyme is raised in several situations, comprising tuberculosis and sarcoidosis as well as leukemia.

Utilized for differential diagnosis of leukemia.

Note:

Lysozyme is a bacteriolytic enzyme that is established in some hematopoietic cells. It mainly exists in granulocytes, monocytes, and histiocytes. The enzyme exists in only minute quantities in lymphocytes; and is not exist in myeloblasts, eosinophils, and basophils.

Lysozyme in the plasma reaches chiefly from the deterioration of granulocytes and monocytes and its concentration contemplates the turnover of these cells. Elevated levels are noticed in benign (eg, infection, inflammation) and cancerous processes(eg, some leukemias). Plasma lysozyme is high in individuals with acute or chronic granulocytic or monocytic leukemias and declines with booming therapy. Contrarily, an individual with lymphocytic leukemia may have low plasma lysozyme levels.

Individuals with kidney infections (comprising rejection of transplanted ren) or Crohn’s disorder (regional enteritis) also manage to have boosted grades of plasma lysozyme.