KRAS Somatic Mutation Analysis Test Cost & Procedure

With the help of this test, particular KRAS gene mutations can be found in the DNA of cancerous cells and tissues. These mutations may be a sign that specific medications won't work well to treat the malignancy. KRAS is the abbreviation for the gene. Kirsten viral oncogene homolog in rat sarcoma.

Why Take a Test?

To find a KRAS gene mutation in tumour samples to direct cancer treatment and assess prognosis.

What is the test used for?

• To help with cancer treatment, this test looks for the most prevalent KRAS gene mutations in the DNA of tumour cells.
• Anti-EGFR therapy is not effective in treating tumours that have the KRAS mutation.
• Tests for other less common mutations not found by the current test that is not present in your tumour may be utilized to predict therapy outcomes if your tumour is negative for the most prevalent KRAS mutation.

When did you order it?

• When you are told that you have non-small cell lung cancer or metastatic colon cancer, a KRAS mutation test is typically required. It could be carried out at any point before the start of the treatment.

What does the test's outcome indicate?

• You won't benefit from EGFR-targeted medicines if the cancer tissue you've given tissue samples from has a KRAS mutation.
• Although the existence of a particular mutation cannot foretell how severe or aggressive cancer will be, the presence of a KRAS mutation also suggests a likely worse prognosis.
• Although the absence of a KRAS mutation as confirmed by the KRAS test does not guarantee that your cancer will react to anti-EGFR therapy, a negative KRAS test result suggests that your disease may.
• A negative test result could happen if there is not enough tumour tissue sample or if some of the cancer cells in the tumour have the mutation while others do not.
• There may also be KRAS mutations that, due to their specific location in the DNA, escape detection by some assays. Cancer that is resistant to anti-EGFR medications may also be brought on by other reasons.