Single antigen bead (SAB) assay is the vastly sensitive instrument obtainable for noticing HLA antibodies and determining the immunological chance for an organ transplant. What is a single antigen bead examination? The single antigen bead examination is the most susceptible and distinct solid-phase quiz for specifying HLA antibodies in...
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Single antigen bead (SAB) assay is the vastly sensitive instrument obtainable for noticing HLA antibodies and determining the immunological chance for an organ transplant.
The single antigen bead examination is the most susceptible and distinct solid-phase quiz for specifying HLA antibodies in patient serum. Identical to the Luminex Panel Reactive Antibody Screen, single antigen bead panels are assembled up of solid phase microspheres packed with varying quantities of fluorescent dye.
Antibodies that catch HLA-G can be employed in numerous scientific applications, comprising Immunohistochemistry, Flow Cytometry, Western Blot, ELISA, and Immunocytochemistry. These antibodies mark HLA-G in Human, Rat, and Mouse specimens. Our HLA-G monoclonal and polyclonal antibodies are formulated in Mice and Rabbits.
This analysis is operated for the determination of before & after-transplantation HLA antibodies in the solid transfer of organ receivers and unmatched Bone marrow transfers. It notices Ab contrasting HLA Ag including HLA- A, HLA-B, HLA-C, DR, DQA1, DQB1, DPA1, and DPB1.
The preface of single antigen bead (SAB) assays for determination and quantitation of HLA antibodies has enhanced our proficiency to recognize and organize all sensitized transplant nominees and recipients and to enhance organ allocation which was essential to the composition of national paired kidney exchanges.
The precise understanding of SAB tests instructs the relation of numerous characteristics, comprising a designation of epitope reactivity ways, mean fluorescence intensity (MFI) esteems, patient history, and preference of respective bead and assay nuances. The Mean fluorescence intensity value delivers an assessment of relative HLA antibody grades although fixed by saturation and epitope distribution impacts.
>> Specialty: Nephrologist
Exporting Stability: Room Temperature: 360 min, cold storage:3 days, chilled: 7 days.
|Test Type||HLA Single Antigen Bead Assay For Class 1 IgG Antibodies; DSA-SAB Class 1|
HLA Single Antigen Bead Assay For Class 1 IgG Antibodies; DSA-SAB Class 1 Test (Nephrology)
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