HLA Narcolepsy (DRB1*15, DQB1*06:02, DQA1*01:02) Test and Its Price in India

This Test is used for the diagnosis of Narcolepsy, which is an extreme condition of Sleep disorders.

HLA-DQB1:

The human leukocyte antigen family has this as its member. This helps detect the body's cells and foreign substances to the antibody.

This gene helps in instructing the immune system about the formation of proteins.

HLA (Human Leukocyte Antigen):

The immune system is used to locate whether the cell belongs to you. It is a type of genetic typing; it is also called HLA Matching. This test can detect whether the patient can safely donate Bone marrow or organs. 

What is MHC?

HLA is a tumour antigen to T cells for the immune system. Antigens bind to proteins for the release of antibodies for the immune system. It assists the body in the quarrel against infection.

HLA Antibodies:

HLA antibodies are made during pregnancy in women when they receive blood from a donor. HLA antibodies do not have any risk. The donated plasma is fatal.

Narcolepsy:

Many nervous disorders are there, and it is one of these types. Patients suffering from this disease have the HLA-DQB1*06:02 allele haplotype. In this disorder,  the brain's activity is disturbed, losing its capacity to stay, and waking is lost.

With proper care and precautions, this disease can be cured.

Causes of narcolepsy:

The significant reasons for Narcolepsy are:

• Deficiency of brain Chemical Hypocretin
• Weak Immune system
• Hormonal Imbalance
• Psychological Stress
• Infection
• Swine flu

Symptoms are seen in Narcolepsy:

• Excessive Sleep in daytime
• Sleep attacks
• Sleep Hallucinations
• Sleep Paralysis
• Muscle Weakness

Types of Narcolepsy:

• Narcolepsy Type-1: This involves sleep attacks
• Narcolepsy Type-2: This does not experience Sleep Attacks.

Deficiency of Hypocretin:

Sleepiness is caused due to this.

The weakness can be seen in the brain cortex, tonsils and nasal mucosa.

Treatment Of Narcolepsy:

Narcolepsy has no medicine to date; only some symptoms can be controlled if properly treated.