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This test is exclusively done for HLA typing of a minimum of four digits in the transplantation of Bone marrow.
It is a gene that lies on 3Mbp on chromosome 6. It is known to be polymorphic.
The immune system is used to locate whether the cell belongs to you. It is a type of genetic typing; it is also called HLA Matching. This test can detect whether the patient can safely donate Bone marrow or organs.
HLA antibodies are made during pregnancy in women when they receive blood from a donor. HLA antibodies do not have any risk. The donated plasma is fatal.
Typing of human leukocyte antigen. Some factors related to the immune system are associated with HLA typing. This test will help to identify the person to whom they can safely donate bone marrow, organs or cord blood to someone who needs to transplant.
The most crucial purpose of HLA typing is to identify the person who can provide the safest bone marrow or any organ for transplantation. NGS-based HLA typing gives high-resolution matching, which can provide high-resolution, phase-defined HLA DNA sequences unambiguously and helps to avoid limitations compared to the traditional line-based Typing methods.
There are four methods:
HLA genes are inherited. It seems like coloured strings. There are various HLA genes.
The potential donor sample is compared with the recipient and will decide the typing result. Results show how many antigens are matched to the donor and how many antigens match the donor. If there are 0 mismatches, it will indicate that the organ donated by the donor to the recipient is safe to transplant an organ or bone marrow or any cord blood, and there is significantly less chance of being rejected by the recipient.
Bone marrow transplants can pose numerous risks. Some severe problems are seen in some patients, and others are expected. Sometimes difficulties are life-threatening.
Bone marrow transplants are done with the donor's healthy blood. Chemotherapy is used to pre the pare the body of the patient
This is a condition in which the patient's immune system attacks the transplanted tissue.
Antigens bind to antibodies which are used to fight against infections.
When the patient receives a transplanted organ, it is considered a foreign body for body. The antigens present on them are considered to be not matched by the body as it is different.
To obstruct this reaction, doctors match the organs.
Various medicines are used to deprive their immune system.
This is one of the most expensive and time-consuming tests. This does not require any such special preparation.
| Test Type | HLA DNA High Resolution Typing - A Locus |
| Includes | HLA DNA High Resolution Typing - A Locus Test (Hematology) |
| Preparation | |
| Reporting | Within 24 hours* |
| Test Price |
₹ 6240
|
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