Histopathology Direct Immunofluorescence Skin Biopsy, IgA Test and Its Price in India

This test is exclusively used to detect the existence of immunoglobulin complexes in.

• SLE(system lupus erythematosus)
• Bullous diseases
• Epidermolysis bullosa
• Herpes 
• Vasculitis

Skin:

Skin is a part of the immune system of the body. It also provides a protective covering around the body. Any disease associated with skin is seen over the skin, which can be detected with the help of skin.

The various diseases which this test can detect are. 

Subepidermal Blister: It includes subepidermal clefting.

• Bullous pemphigoid (BP)
• Cicatricial pemphigoid
• Epidermolysis bullosa  (EBA)
• Bullous lupus
• Linear IgA

Intraepidermal Blisters:

• Pemphigus Bulgaria
• Pemphigus foliaceus
• IgA pemphigus

Connective Tissue disease:

• Lupus erythematosus
• Dermatomyositis
• Vasculitis
• patient

What is lupus systemic erythematosus?

The body's immune system is affected, an inherited disease affecting older adults.

Bullous Diseases:

Itchy rashes are seen in this disease and affect adults.

Vasculitis

When the body's blood vessels get inflamed, this condition is known as Vasculitis. Vasculitis can affect all the blood vessels starting from tiny blood vessels to large blood vessels.

When the blood vessels get inflamed, their blood becomes weak and stretches in size.

Symptoms of vasculitis

Common symptoms include:

• Skin rashes
• Fatigue 
• Weakness
• Disruption

What is a biopsy?

It is a diagnostic procedure in which a portion of tissue of the diseased organ is taken and examined under a microscope.

Immunofluorescence Test

This test is used in labs to detect various diseases of the skin, heart,  kidney, and other organs.

In this test, a unique bar pairing occurs between antigen and antibody to identify the proteins in the blood sample.

It is a microscopic method used to detect diseases.

Types of immunofluorescence

• Direct immunofluorescence
• Indirect immunofluorescence

Direct Immunofluorescence

This type of immunofluorescence uses a single antibody, which is linked to a fluorophore. This antibody identifies the marked molecule and binds to it. The microscope identifies this bonded molecule.

Why is this test used?

Immunohistology with histology aids in detecting various skin disorders like systemic lupus erythematosus. The immunofluorescence test has become the best way to diagnose a skin disorder.

The procedure of Biopsy:

• The tissue biopsy sample is taken.
• The piece is inserted into Michel's transport Media