Hemoglobin (Hb) D Punjab Test Cost & Procedure

Utilizing end point PCR technology, the hemoglobin D Punjab(HbD) Mutation Study is carried out. For this test, a sample of amniotic fluid, chorionic villi, and cord blood must be provided in a sterile container, a sterile normal saline container, or an EDTA vacutainer (2 ml). Results should be visible in 7-8 days. Describe hemoglobin.

Four linked protein molecule configurations known as globin chains make up hemoglobin.

Hemoglobin D-Punjab disease: what is it?

• Serious health problems are caused by sickle and D-Punjab hemoglobins. A surplus of Hb D can lead to moderate anemia by reducing the size and quantity of RBCs. In most cases, Hb D illness does not result in major health issues.
• A mutation in either or both of the best betachainsat that make up hemoglobin molecules results in hemoglobin D.
• Although the symptoms of this "illness" are modest, having two afflicted genes is referred to as homozygous while having one impacted gene is referred to as a characteristic.
• The Los Angeles region is where hemoglobin D-Punjab, often known as "D Los Angeles," was originally identified in a mixed British and American family with Indian ancestry.
• The fourth most typical hemoglobin variation is hemoglobin D.
• As a result of the selection pressures of malaria in various parts of Asia, it evolved.

Techniques for Hemoglobin Tests:

• Typically, the specialist draws blood from a vein to administer the test.
• An infant's heel can be used to draw blood using a little needle (lancet).
• An elastic band (tourniquet) is wrapped around the upper arm to exert pressure and cause the veins to swell with blood before blood is extracted from the vein.
• The skin is then cleaned with an antiseptic before the needle is inserted and blood is collected from the vein.
• Both the band and the needle are removed after this surgery. The specialist will apply a bandage or cotton to halt the bleeding.