DNA Ploidy and S-Phase (Solid Tumors) Test Cost & Procedure

This test aids in the prognosis of cancer. Compared to diploid tumours, aneuploid tumours typically have a worse prognosis. It may help determine the likelihood of malignancy in certain tumour specimen types.

Where possible, the tumor-specific S-phase is employed.

For diploid, near-diploid, and hypodiploid malignancies where the tumour and host S-phases cannot be distinguished, an average histogram S-phase is utilised. When the proportion of aneuploid cells in the histogram is minimal, the S-phase average histogram is also used (less than 25 percent).

Describe the DNA ploidy test

In DNA ploidy analysis, the DNA content per nucleus for every nucleus from a tumour specimen is calculated to produce a histogram of the DNA content distribution in the measured sample.

What is cancer's S phase?

DNA synthesis (S phase)

The number of chromosomes is altered in many cancer cells, resulting in either an excess or a deficiency of chromosomes in the cells. The term "aneuploid" refers to these cells. DNA replication mistakes could lead to mutations and the potential emergence of cancer.

What are cancers?

Uncontrolled cell growth causes malignancies, which cause cancer in the affected area. While some cancers are hereditary or inherited and the result of a genetic mutation, the majority of cancers are random and happen by chance. Changes in the DNA sequence lead to conversions.

A cancer gene panel: what is it?

A laboratory examination in which any genes are examined in a tissue sample. Multiple-gene panel testing aid in identifying gene mutations (changes) that may raise a person's chance of developing diseases like cancer. They might also examine the expression of particular genes in a tissue sample.

Why is this examination suggested?

The type of tumour and tissue source impact more than the diagnostic and prognostic value of tumour DNA. If the tumour has any available interpretation data.

What is flow cytometry?

This is used to locate Tregs. It uses lasers to help analyse the chemical and structural properties of cells.

Uses

• Identifying the properties of cells
• The bacteria's identification
• Organising cells
• Cell identifying
• Discovery of bone marrow malignancy
• Learn about the biomarkers

Procedure

• Once the investigational cells are added, the fluid is coloured with particular colours.
• The substance is brought to a standstill in the flow cytometer.
• The laser of the flow cytometer highlights the features of the cells.
• Then they are interpreted by a computer.
• The creation of graphic data follows.