Burkitt Lymphoma-Translocation 8/14 Test Cost & Procedure

Burkitt Lymphoma-Translocation 8/14 Chromosome translocations, a type of lymphatic system cancer, cause Burkitt lymphoma. A chromosome is fragmented during a chromosome translocation, after which it becomes linked to pieces of other chromosomes. The most frequent variation, which makes up roughly 85% of cases, is t(8; 14). As a result, Burkitt lymphoma-Translocation 8/14 is the name of the blood test.

Tumors of the jaw or other facial bones are the initial sign of some Burkitt lymphoma symptoms. Chemotherapy, bone marrow transplants, stem cell transplants, surgery, and radiotherapy are a few treatments for Burkitt lymphoma.

Burkitt lymphoma-Translocation 8/14 Test: What Is It?

• A malignancy of the lymphatic system, namely B lymphocytes located in the germinal center, is called Burkitt lymphoma.
• B cells, the type of lymphocytes the immune system employs to produce antibodies, are the source of the solid tumor.
• Chromosomes contain the genes needed to produce antibodies. Only B lymphocytes may express some genes, such as 14 (the heavy [H] chains), 2 (kappa light chains), and 22 (lambda light chains) since only B cells have the transcription factors required to turn certain antibody genes "on."

Burkitt lymphoma-Translocation 8/14 Test Preparation:

Such planning is not required. Burkitt lymphoma-Translocation 8/14 Test Applications

Burkits have a high propensity to expand to lymphoma, and CNS, hence systemic chemotherapy is given in addition to intrahepatic chemotherapy using methotrexate, ARA-C, and/or prednisolone.

Burkitt lymphoma-Translocation 8/14 Test Procedure:

• Intense chemotherapy is the first stage in the healing process.
• The time of the diagnosis affects the effects of chemotherapy in all cancers.
• Cancer that is growing quickly, like Burkitt's, responds to chemotherapy much more quickly than cancer that is growing slowly.
• However, this severe response to chemotherapy poses a risk to the patient due to a condition known as "Tumor Lysis Syndrome."

Throughout this process, it's crucial to keep an eye on the patient and drink enough water. Burkits have a high propensity to expand to lymphoma, and CNS, hence systemic chemotherapy is given in addition to intrahepatic chemotherapy using methotrexate, ARA-C, and/or prednisolone