BRAF V600E for Hairy Cell Leukemia Test Cost & Procedure

BRAF V600E for Hairy Cell Leukemia

BRAF V600E for Hairy Cell Leukemia

Book BRAF V600E for Hairy Cell Leukemia Appointment Online at the best price in Delhi/NCR from Ganesh Diagnostic. NABL & NABH Accredited Diagnostic centre in Delhi offering a wide range of Radiology & Pathology tests. Get Free Ambulance & Free Sample collection from Home. 24 Hour Open.

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Normal cells may become cancer as a result of BRAF gene mutations. BRAF mutations can be discovered in various types of cancer, however they are more frequently found in melanomas. Not all BRAF mutations result in cancer.

Describe BRAF.

The gene BRAF, which is located on chromosome 7, produces a protein with the same name. This protein promotes cell division among other tasks inside the cell, contributing to cell development.

A BRAF mutation is what?

A mutation makes the gene activate the protein and keep it active, which results in some cells receiving constant impulses to divide and no guidance on when to stop.

BRAF mutations come in many different forms, according to researchers. The BRAF V600E modification is one of the most accurate varieties. The mutation's kind and location are indicated by the name V600E:

The mutant amino acids (which make up proteins) are represented by the letters V and E. In this instance, glutamic acid (GA) took the place of valine (V) (E).

The amino acid number 600 in the protein is where the mutation occurred, hence the number 600.

Various targeted medicines may respond differently to various BRAF mutations. Some BRAF mutations are resistant to specific targeted treatments.

What is the connection between cancer and the BRAF modification?

When combined with other mutations or external conditions, certain BRAF mutations can result in cancer. BRAF mutations, either by themselves or in conjunction with other mutations, can also accelerate the growth of malignancies.

The malignancies linked to the BRAF gene mutation are not restricted to a particular organ system or cell type. Among these cancers are:

Melanoma (approximately half of all melanomas have the BRAF gene mutation) (about half of all melanomas have the BRAF gene mutation)

  • Hairy cell lymphoma
  • Hodgkin lymphoma
  • the thyroid cancer
  • Uterine cancer
  • Lethal lung cancer
  • carcinoma of the colon

Many types of brain cancer, such as juvenile low-grade glioma, pilocytic astrocytoma, and glioblastoma

The BRAF mutation inherited?

The majority of the time, a BRAF mutation linked to cancer developed during the course of a person's lifetime. This mutation, however, only affects the cells in which the alteration has taken place and cannot be passed on to your children. BRAF mutations can be inherited in a relatively small number of cases (passed on from a parent). A mutation that is already present at birth may have a major negative impact on the body's cells and other bodily functions.

Test Type BRAF V600E for Hairy Cell Leukemia

BRAF V600E for Hairy Cell Leukemia (Pathology Test)


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