Any 3 Cancer Marker - Book Test at Low Cost

The term "tumour marker" refers to any substance that is present in or produced by cancer cells, other cells of the body, or certain benign (noncancerous) conditions in order to provide information about a tumour, such as its aggressiveness, its ability to be treated with targeted therapy, or its response to therapy.

Although they function as tumour indicators for just a portion of cancers, some of the tumour markers described below represent targets for targeted therapy in several tumours.

Rearrangements and overexpression of the ALK gene

cancer kinds or illnesses that resemble cancer: Histiocytoses, anaplastic large cell lymphoma, and non-small cell lung cancer

What is examined: Tumor

How applied: for guidance on diagnosis, prognosis, and therapy

Alpha-fetoprotein (AFP) 

Liver cancer and germ cell tumours are two cancer forms.

Analysis of: Blood

How applied: To aid in the diagnosis of liver cancer and track treatment response; to evaluate the stage, prognosis, and treatment response of germ cell cancers

Rearrangement of the B-cell immunoglobulin gene

Kind of cancer: B-cell lymphoma
What is examined: Tumor tissue, bone marrow, or blood
How applied: to aid in diagnosis, assess treatment success, and look for recurrence

BCL2 gene reorganisation

Types of cancer: lymphomas and leukaemias
What is examined: Tumor tissue, bone marrow, or blood
How applied: For diagnostic and therapeutic planning

Beta-2-microglobulin (B2M) 

Multiple myeloma, chronic lymphocytic leukaemia, and a few lymphomas are cancer types.

What is examined: urine, cerebrospinal fluid, or blood
How applied: to ascertain prognosis and monitor treatment response

Which types of cancer are now treated with which tumour markers?

Currently, a variety of tumour markers are being employed for a variety of cancer types. Although the majority of these may be evaluated in facilities that adhere to the Clinical Laboratory Improvement Amendments' criteria, some cannot, and therefore might be regarded as experimental.

What role do tumour markers play in cancer treatment?

Circulating tumour markers and tumour tissue markers are the two primary categories of tumour markers.

Some cancer patients' blood, urine, stool, or other body fluids may include circulating tumour markers. Using circulating tumour markers, one can:

forecast prognosis

establish the tumour's stage and identify any cancer that has recurred or that has remained dormant despite therapy

evaluate how well a treatment is functioning and keep an eye out for signs that it has ceased working

High Level Of Tumor Marker

Although though a high level of a circulating tumour marker may indicate the presence of cancer and help with the diagnosis, it is insufficient to make the diagnosis on its own. A higher level of a tumour marker particular to that cancer will not always be present in all cancer patients with a particular type of cancer. To ascertain the existence of cancer, circulating tumour marker values are often combined with the results of other procedures, such as imaging or biopsies..