What does an amyloid protein test entail? An acute-phase protein called serum amyloid. It is involved in the aetiology of atherosclerosis. The study's objective was to determine the level of SAA in RA patients' serum in relation to other inflammatory parameters and indicators of...
An acute-phase protein called serum amyloid. It is involved in the aetiology of atherosclerosis. The study's objective was to determine the level of SAA in RA patients' serum in relation to other inflammatory parameters and indicators of extra-articular involvement.
1. An initial pathology report and medical history are needed.
2. It's also advised to send a quick letter of explanation or consultation.
Collection Instructions: Don't send tissue slides that have been repaired. Only blocks of tissue with paraffin embedded can be tested.
Prior to mass spectrometry testing in every case with sufficient tissue, a preliminary Congo red stain is carried out to confirm positivity.
Normally, a pathology consultation is not necessary. Upon client consent, a PATHC / Pathology Consultation may be added if necessary in the event that the results of the amyloid subtyping do not match the clinical findings.
Laboratory Methods for Diagnosing Amyloidosis: Pathology Consultation Ordering Algorithm
Name of the procedure Liquid chromatography-tandem mass spectrometry with histological stain
The extracellular tissue deposition of misfolded proteins that causes end organ damage unites the hereditary and acquired disorders known as amyloidosis. The disease amyloidosis can be either systemic or localised. Despite the fact that many cases of amyloidosis are genetic, the majority are acquired due to underlying monoclonal B-cell/plasma cell cancer, as a result of age, or as a result of long-term chronic inflammation. Thus, particular amyloid proteins are linked to particular amyloid-related illnesses. These include serum amyloid A (SAA amyloid), transthyretin (ATTR amyloid), kappa or lambda immunoglobulin light chains (AL amyloid), and other unusual variants. Accurate identification of the proteins that make up the amyloid deposits is crucial since the therapy of patients with amyloidosis varies greatly depending on the many amyloid subtypes.
|Test Type||Includes||Preparation||Reporting||Test Price|
|Amyloid Protein Typing||
Amyloid Protein Typing (Pathology Test)
Within 24 hours*
Early check ups are always better than delayed ones. Safety, precaution & care is depicted from the several health checkups. Here, we present simple & comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.