IHC - MLH1 Test - Book at an Affordable Cost

The MLH1 gene produces a class of proteins called MLH1 that is typically found in the human genome. One of the seven MMR proteins, MLH1, works cooperatively to repair DNA mismatches in the human body.

About 13% of collateral cancers are caused by DNA mismatch defects, with MLH1 being more common than the other MMR proteins. Additionally, the MLH1 protein significantly contributes to human tumors, particularly in the stomach. One of the main risks associated with gastric cancer is MLH1, which is immunoreactive with MGMT in nearly 135 specimens.

Requirement for test

• Formalin-fixed, paraffin-embedded tissues must be identified and marked on the patient's body to prevent contamination of the sample extract region.
• The patient should be made aware of the benefits and drawbacks of the test and any associated complexity in advance. The patient should be free from preconceived notions regarding the examination and sample collection process. Before the test and sample collection, clean surroundings, well-stained slides, and needles should be kept.
• The edges of the sample extraction region and the stained area should be cleaned with a very tidy and clean cotton cloth.

IHC MLH1 Test Applications

Tumors are one of the most common diseases that can result from a protein deficit in a person's body, but there are other disorders. Lynch syndrome can be identified through the interpretation of the IHC MLH1.

IHC MLH1 procedure

It is best to choose a broad needle with good extraction compatibility. 15–20 ml of the serum must be withdrawn from the tumor ball using a hand, collected in a tidy tube, and transported to the actual testing site.

What is the Cost of Immunohistochemistry (IHC) - MLH1 Test

The average price for Immunohistochemistry (IHC) - MLH1 test is seen to differ from one center to another. The price range is said to be between INR 2000 to INR 12500 in Delhi, India.