Cell-Free Tumor DNA Test Cost & Procedure

DNA in plasma is called CfDNA. Although longer fragments have been seen, they are typically 50 to 200 base pair long, double-stranded fragments. These fragments are created when cells are broken down by the body and then die as a result of disease or aging.

What do you mean by liquid biopsy?

It aids the detection of cancer. Using liquid biopsies is advantageous in:

• cancer cells
• tumor DNA in motion

CfDNA: what is it?

Circulatory-free DNA screening is what it is called. Patients with higher levels of cfDNA exhibit cancer signs and may experience cell necrosis.DNA from cancerous cells and tumors that are circulating in the bloodstream is referred to as "circulating tumor DNA" (ctDNA). As a tumor grows, cells depart and are replaced by fresh ones.

The broken-down dead cells discharge their contents, including DNA, into the bloodstream. The amount of ctDNA varies from person to person and is influenced by the type of tumor, its location, and, in the case of malignant tumors, the stage of the disease.

The following circumstances call for the use of ctDNA detection:

• identifying and treating a tumor.
• The ctDNA does not exactly match the person's DNA since tumor DNA has undergone numerous genetic alterations (variants) that have contributed to the development of tumors.
• Tumor identification is aided by discovering DNA with genetic variations.
• When a tumor is difficult to access, like a tumor in the brain or lung, determining the kind of tumor using ctDNA can eliminate the necessity for obtaining a sample of the tumor tissue (tumor biopsy). the direction of tumor-specific treatment.
• Doctors can decide on the best course of treatment by analyzing the tumor cells' genomes using ctDNA. However, the U.S. Food and Drug Administration has not yet approved ctDNA testing to individualize cancer treatment. therapeutic supervision.
• A drop in ctDNA levels indicates that the tumor is getting smaller and that the treatment is working. The bloodstream's lack of ctDNA is proof that cancer has not come back.