The Tuberculosis (TB) is known to be a contagious infection that is known to usually attack lungs of the individual. It has spread to different parts of your body, like your brain and spine. This type of bacteria is called Mycobacterium tuberculosis and to understand what causes it.

The Active Form: The Tuberculosis (TB) disease could occur in the various anatomical sites, but this will be divided into the two main groups, such as the pulmonary TB disease and any extra pulmonary disease. Because the TB disease predominantly affects the lungs, this form is also commonly referred to as your pulmonary disease.

Diagnostic Testing Procedures for TB

1. Bacterial culture

Your MTB is slow growing in nature. Due to any challenges of the cultivation, use of just one liquid and one of the solid media is recommended further to maximize the recovery process.

2. Advanced testing methods

The most widely used US FDA-cleared automated systems for any rapid detection of the mycobacteria using the liquid media would include:  BacT/ALERT 3D (Biomerieux), the BACTEC MGIT (Becton Dickinson) and the VersaTREK (Thermo Fisher).

These employ automated continuous monitoring of carbon dioxide (CO2) production or oxygen (O2) consumption to detect MTB.

3. Nucleic Acid Tests in TB

Your Xpert MTB/RIF is known to utilize the nested real-time PCR for any qualitative detection of MTB complex and the RIF resistance. The diagnostic algorithm using NAAT serves as an initial diagnostic test in which the pending culturing is shown.

The Rapid turn-around time for the NAAT test and AFB test is necessary for the diagnosis and your prompt initiation of your therapy pending culture results

Conclusions of these Advanced Tests

Common target genes for TB by NAAT , the Various genes are targeted by NAAT.

Apart from that, there are 2 more tests for tor TB. Such as: There interferon gamma release assays (IGRAs) that have been approved by FDA and are available. for TB screening. The tests listed are as follows:

• QuantiFERON TB Gold In-Tube test (QFT-GIT)
• T-SPOT TB test (T-Spot)

What is the requirement of these tests?

If you experience the following TB symptoms, make sure to get yourself tested for TB using the advanced testing procedures as mentioned above.

• Fatigue
• Chest Pain
• Night Sweats
• Blood Cough
• Chills
• Cough lasting > 2 weeks

Note: Tb has the ability to affect not just the lungs, but other parts of the body as well. E.g. Brain, spine etc

Risk Factors

Have HIV or another disease that weakens your immune system

• The illicit use of illegal drugs
• The higher rate of your  TB infection in enclosed spaces, example- prison or the nursing home
• Any specific medicines would suppress the immune system

Tests Results Interpretation

• Inactive (latent) TB-This means TB bacteria are present in your body but are not active and are not causing symptoms. You are not contagious, although it's possible for you to develop TB in the future.
• Active TB or TB disease- This means TB bacteria are active in your body, and you are contagious.

Guidelines to follow before, during and after the TB Testing

Here are some guidelines an individual can refer to once they have decided to undergo TB Tests in Ganesh Diagnostic and Imaging Center

The required documents needed for this test includes your valid government ID and an appropriate Doctor’s prescription.

A. Before the Test

The preparation for multiple tests for TB testing may require some preparation ahead.

Usually, Fasting is not required before the test. But, it is recommended to consult your doctor before undergoing advanced TB Tests

B. During the Test

During the blood test, the doctor would take the blood sample from the vein in your arm, using the small needle.

Then, a small amount of blood would be drawn and collected into the corresponding test tube or the vial.

You might feel a little sting when the needle pricks or while it is being removed. This would usually take less than even five minutes.

C. After the Test

There would be slight tenderness at the injection site without any major concern. This patient is expected to get back to their daily life immediately.

For Free Consultation from the Doctor

Contact- Dr. Ravin Sharma, (MBBS, MD in Radiology)

Available:  24*7*365

Phone Number: +919212125996

Are there any risks to this test?

There could be risks seen that are as follows:

• Bleeding
• Infection
• Bruising
• Feeling Lightheaded

How is tuberculosis treated?

Your TB infection and this disease is said to usually be treated with the following drugs:

1. Isoniazid (Hyzyd®).
2. Revampingz (Rifadin®).
3. Ethambutol (Myambutol®).
4. Pyrazinamide (Zinamide®).
5. Rifapentine (Priftin®).

Note: You are recommended to take all the medication that the healthcare professional would prescribe, or not all of your bacteria would be destroyed

You should consume these medications for as long as advised from 9 to 12 months.

1^st line of treatment: Out Of these approved drugs, the ones mentioned above, such as: isoniazid (INH), rifampin (RIF), ethambutol (EMB), and pyrazinamide (PZA) are considered to be the first-line anti-TB drugs and thus, they form the core of this standard treatment regimens

While, Rifabutin (RBT) and rifapentine (RPT) might be considered first- line drugs under some certain circumstances.

Directly Observed Therapy (DOT)

It is usually seen that the DOT treatment is one of the most preferred core management strategy would be recommended by the CDC for your treatment of the TB disease and at times also for latent tuberculosis infection (LTBI) treatment.

Nearly, all treatment regimens that are drug-susceptible TB disease would be given intermittently if they are directly observed.

Note: The Drug-resistant TB disease should be considered as a daily regimen and under the direct observation.

There are also no intermittent regimens for the treatment of the multidrug-resistant (MDR) TB.

Fixed-Dose Combination Drugs

The use of this fixed-dose combination capsules or the tablets facilitates this DOT administration by minimizing chance for any error through the even use of fewer tablets and this might reduce the risk of any acquired/ Multidrug resistance (MDR) since one of the medication that cannot be selectively taken.

Self-Administered Therapy

Patients on their self-administered therapy should be monitored routinely for Patient Adherence and further follow-up visits.

Why should Ganesh diagnostic and Imaging Centre be your preference for getting Tuberculosis Test done?

At Ganesh Diagnostic and Imaging Centre, we are known for providing excellent service and care to its patients for decades. Lakhs of satisfied patients over the years!

It is an established and renowned diagnostic centre since 2001.

Their excellence is backed by NABH and NABL Accreditations. 

NABH accreditation is proof of highest standard of care and service provided to the patients. NABL accreditation reflects the competency of laboratories and equipment based on some national and international standards.

Test report is available digitally too.

Ganesh Diagnostic and Imaging Centre is a one-stop solution for getting all kinds of tests done, as all services are available under one roof.

The aim of GDIC is to provide world’s finest technology at the lowest price. 

The rates of scans are reasonably priced. Ganesh Diagnostic and Imaging Centre also offer FLAT 50% OFF on many tests. 

Patients can rely upon test reports as reports are 100% accurate.

The cost of the TB Tests in Delhi, at Ganesh Diagnostic and Imaging Center are as follows.

The Tests that are conducted at Ganesh Diagnostic and Imaging Center are as follows:

• AFB-Identification & Speciation MTB and MOTT by Hains
• GeneXpert MTB with Rifampicin Sensitivity, Qualitative PCR.
• GeneXpert MTB with Rifampicin Sensitivity, Quantitative PCR
• Genexpert Ultra (Next Generation) MTB PCR
• PCR TB For Semen
• QuantiFERON - TB Gold
• SPUTUM (CB NAAT) GENE X-PERT

Cost of TB Advanced Tests in Delhi

The Serum Blood Tests vary by region and facility. So constantly get tested at trustworthy diagnostic centers like Ganesh Diagnostic. It is staffed by trained and experienced professionals to assure patient and visitor safety.

There are multiple tests that are done to monitor any Hormonal issues leading to TB Advanced Tests

So get your TB Advanced Tests done your nearest Ganesh Diagnostic Center.

Book Your Online Test and Get Early Appointment

Ganesh Diagnostic Center promotes great care and concern for patients.

It is our utmost duty to allow a speedy diagnosis and hope that in future, your treatment is done at the earliest.

Thus, we recommend you to book an appointment with us today and book your online blood test for any specific disease, disorder and discomfort.

Avail our digital support system and establish a long lasting relationship with Ganesh Diagnostic Center near you today. Book Now!

Note from Ganesh Diagnostic & Imaging Center

Early checkups are always better than delayed ones. Safety, precaution & care are depicted in the several health checkups at our center.

Here, at Ganesh Diagnostic and Imagining Center, we present simple and comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.

So, visit us at the earliest to ensure good health and to maintain an active immune system

Frequently Asked Questions (FAQs)

What sample is used for CB NAAT test?

The Cartridge Based Nucleic Acid Amplification Test (CBNAAT) is known to be a rapid molecular diagnostic test. It is mostly used in the diagnosis of your Tuberculosis (TB) and any Rif-resistant Tuberculosis (RR-TB) in your NTEP. The results are mostly obtained from any unprocessed sputum samples which is in about 2hours and this helps in the early detection and treatment of any TB patients.

What is the effectiveness of CBNAAT in the diagnosis of extra pulmonary tuberculosis?

The Cartridge-based nucleic acid amplification test (CBNAAT) is considered to be a very useful assay for any early diagnosis of the extra pulmonary cases. This would accurately identify the false negative samples by the smear microscopy.

How does the Genexpert work in testing for TB?

The Genexpert diagnoses TB by detecting the presence of TB bacteria. The test is a molecular TB test which it detects any DNA in the TB bacteria. It uses the sputum sample and this would show the results in less than a time period of 2 hours.

How sensitive is GeneXpert in urine?

The GeneXpert MTB/RIF, the real-time PCR, is a sensitive and a specific test with around 131 cfu/mL limit of any detection that also allows for any early detection of the TB disease. The AFBs are known to intermittently shed in your urine and your sensitivity of the GeneXpert . This could be improved by using the early morning urine for any extended periods ranging from around 3 to 5 days.

What happens if GeneXpert is negative?

There is an enhanced accuracy and it has a negative predictive value of the GeneXpert, which was found to be extra better than the AFB staining. Thus, the negative GeneXpert test would be able to rule out your TB. Further, the negative GeneXpert bears a positive smear microscopy, and the results indicate any presence of the NTM.

How can you prevent the spread of TB?

• Wash hands regularly
• Cough by covering your mouth
• Avoid close contact with healthy individuals
• Take timely medications
• Take considerate time off from work and school, until fully recovered.
• Get Vaccinated (BCG vaccine)