PSMA PET Scan, Preparation, Procedure, and the Requirements

26 Oct 2022

PSMA PET Scan, Preparation, Procedure, and the Requirements

What is PSMA PET Scan?

PET PSMA Scan ( prostate-specific membrane antigen scan) is the latest imaging technique for prostate cancer that locate cancer lesions. PSMA PET uses an FDA Approved PET-sensitive drug (68Ga-PSMA-11). This drug attaches to prostate cancer cells and aids in their localization. The most prevalent malignancy among men is prostate cancer. The detection and management of prostate cancer will be greatly enhanced by the novel prostate-specific membrane antigen (PSMA) PET imaging.

How does PSMA PET work?

The patient will be injected with 68Ga-PSMA-11 radioactive tracer medication. This medication binds to PSMA proteins. Prostate cancer tumors overexpress this protein. The PET scan locates the tumors for more precise treatment because it picks up the concentrated PSMA tracer.

How is PSMA PET imaging different from other prostate cancer imaging?

A synthetic radioactive amino acid is injected into patients using a current standard procedure termed fluciclovine PET. It is more accurate prostate cancer detection for improved treatment planning and focused care. It is more efficient in locating and removing cancers that have spread outside of the prostate to other parts of the body and the pelvis.  It can detect significantly more prostate lesions than fluciclovine PET in men who had undergone a radical prostatectomy but experienced a recurrence of cancer. It is a more effective and precise technique for localizing metastatic prostate cancer.

Who should consider PSMA PET?

* Men who have initially been diagnosed with prostate cancer and have a risk for metastatic disease.

* Men who had undergone radiation therapy or prostatectomy, but developed biochemical recurrence as shown by a rising PSA.

What happens during the PSMA PET Scan?

* The radioactive tracer drug 68Ga-PSMA-11 is injected into the patient.  

* The patient is asked to wait for one hour before being scanned.

How long does a PSMA PET Scan take?

* The entire scan procedure takes about 2 hours.

* The procedure of PET scan takes about 30 minutes.

Preparation

Same as PET-CT

Conclusion:- For prostate cancer care, precision diagnosis is imperative for an effective treatment plan. The quality of cancer diagnosis has increased with the help of State-of-the-art technology. It facilitates early detection of the problem and provides sufficient diagnostic information during all stages of prostate cancer and effective treatment planning.