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Anti-CCP Antibody Test : A Complete Guide Regarding Test, Procedure, Preparation and Cost

Anti-CCP Antibody Test : A Complete Guide Regarding Test, Procedure, Preparation and Cost

Rheumatoid arthritis (RA) is a chronic auto-immune disease. It is a multisystem disorder involving the skin, heart, lungs, eyes, nerves, blood vessels and blood cells but primarily affect the joints.

What is CCP Antibody Test?

Rheumatoid arthritis (RA) is a chronic auto-immune disease. It is a multisystem disorder involving the skin, heart, lungs, eyes, nerves, blood vessels and blood cells but primarily affect the joints.

In this condition, our immune system starts forming auto-antibodies that attack the joints and other parts of the body resulting in various presentations, especially chronic inflammation and pain. Rheumatoid arthritis is usually seen in middle age (4th-5th decade) and is 2.5 times more common in women than men.

Anti-CCP antibody test is a specific test for rheumatoid arthritis. It is used for the detection of antibodies against cyclic citrullinated peptide (CCP) in blood/plasma. It is more specific than rheumatoid factor (RF).

Although, anti-CCP is detected in majority of patients with rheumatoid arthritis, a negative result does not exclude rheumatoid arthritis and arthritis if present is called seronegative arthritis.

Anti-CCP test allows the diagnosis of rheumatoid arthritis at an early stage and sometimes even before the symptoms began to appear.

Other names of CCP Antibody test

  • ACPA (anti-citrullinated protein antibodies) test.
  • Anti citrullinated peptide antibody test.
  • Anti citrulline antibody test.
  • Anti-CCP test.

Why do I need an Anti-CCP antibody test?

Your health care provider may order an Anti-CCP antibody test or APCA test if you have symptoms or signs suggesting rheumatoid arthritis such as:

  • Painful and swollen joints.
  • Stiffness in joints limiting movements especially small joints of wrists and hands (PIP, MCP, wrist involved with sparing of DIP joints.
  • Symmetrical involvement of joints that means same joint is affected on both sides of the body.
  • Constitutional symptoms such as low-grade fever, loss of appetite, weight loss, weakness, fatigue.
  • Polyarthritis (multiple joints are involved).
  • Pain typically worsens after rest.
  • Early morning stiffness of joints that lasts for >1 hour.
  • Synovitis.

Deformities such as

  1. Boutonniere deformity/ Buttonhole deformity
  2. Z line deformity or Z thumb deformity
  3. Swan neck deformity
  4. Trigger finger
  5. Hammer toe
  6. Piano-key movement
  7. Hallux valgus
  8. Windswept deformities of toes
  9. Eversion at subtalar joint /hindfoot.
  • Rheumatoid nodules over bony prominences such as knuckles, elbow and heel. 
  • Compression neuropathies such as Carpal tunnel syndrome.

What are the complications of rheumatoid arthritis?

Rheumatoid arthritis is a multisystem disorder affecting almost every system in our body and can lead to a large number of complications such as:

  • Pleuritis
  • Lung fibrosis
  • Caplan’s syndrome
  • Exudative pleural effusions
  • Pericarditis
  • Endocarditis
  • Coronary artery disease
  • Mitral regurgitation
  • Diffuse alopecia areata
  • Episcleritis and scleritis
  • Keratoconjunctivitis sicca
  • Normocytic normochromic anemia
  • Anemia of chronic diseases
  • Osteoporosis
  • Arthritis mutilans
  • Periodontitis
  • Peripheral neuropathy
  • Mononeuritis multiplex
  • Cervical spine disease
  • Myelopathy
  • Vasculitis

Increased risk of

  1. Stroke
  2. Atherosclerosis
  3. Myocardial infarction
  4. Diffuse large B-cell lymphoma
  5. Skin cancers etc.

How do I prepare for Anti-CCP antibody test?

Follow these simple steps if you are going for an Anti-CCP antibody test:

  • Take an appointment: Fix an appointment for Anti-CCP antibody test in a diagnostic lab to avoid waiting at the time of test.
  • Food: You can take your usual meals. Fasting is usually not required for an Anti-CCP antibody test if done alone.
  • Medications: Inform your doctor about all the drugs and supplements that you are currently taking. Certain drugs may alter the test result. Your doctor may advice some modifications before the test if required.
  • Exercise: Avoid strenuous exercise before the test as it may alter test results.
  • Smoking:  Avoid smoking before the test as it may affect the test results.

What is the procedure for Anti-CCP antibody test?

The procedure of Anti-CCP antibody test includes the following steps:

  • First a torniquet will be tied around your arm.
  • Then a cotton swab soaked with 70% alcohol is used to clean/disinfect the injection site before needle insertion.
  • Then a small needle will be inserted in the vein of your arm and required amount of blood is withdrawn from it and collected in a test tube.
  • Then the needle is removed and an adhesive sticker is placed on the puncture site to prevent it from infections.
  • Sample is sent to laboratory for further processing and testing.

Price of Anti-CCP antibody test in Delhi?

Cost of Anti-CCP antibody test depends upon many factors such as city and locality. Different diagnostic labs charges according to the quality of machines they have and various offers that they are providing to their customers.

Ganesh Diagnostic and Imaging centre (GDIC), Rohini also known as GDIC or Ganesh lab is currently offering 50% discounts on various blood tests.

Our centers are NABH accredited and equipped with modern, highly expensive machines with latest cutting-edge technologies and highly skilled Radiologists and Pathologists.We follow strict aseptic conditions to prevent transmission of infections.

Charges of various tests used for the diagnosis and monitoring of Rheumatoid arthritis at Ganesh lab are as following:

Tests included in Rheumatoid Autoimmune Comprehensive Panel:

  • Anti-nuclear antibody
  • Rheumatoid factor
  • Sedimentation rate
  • Uric acid
  • CBC (complete blood count)
  • C-reactive protein
  • Creatine kinase
  • Thyroid panel
  • Metabolic panel

Hurry! Grab the best deals now!

Best diagnostic centre for CCP Antibody test in Delhi?

Ganesh Diagnostic and Imaging center (GDIC) is considered as the best diagnostic lab for CCP Antibody test in Rohini, North-East Delhi. We have many branches in different locations of Delhi including Hari Nagar, Yamuna Vihar, Nangloi, Derawal Nagar and Mangol puri.

Ganesh lab (GDIC) is now considered one of the most popular diagnostic labs in Delhi as:

  • We provide high standard quality services to our patients.
  • Experience of 23+ years of services.
  • Our labs are NABH certified.
  • Facility of latest cutting-edge technologies.
  • Well-trained technicians.
  • Highly Skilled Radiologists and Pathologists
  • Genuine reporting and Patient satisfaction are our top priority.
  • We offer seamless integration between diagnosis and treatment planning.
  • Affordable Diagnostic lab with up to 50% discount on many tests. Currently, we are offering flat 50% discount on various types of blood tests.
  • We are open 24X7 and 365 days.
  • You can also avail free Consultation with our Pathologist regarding any blood test or imaging scans.
  • We also offer facilities of online reporting, free home sample collection and free Ambulance services in Delhi, NCR.
  • We are empanelled with various departments and organizations. So, you can get the services at panel rate too.  
  • Lakhs of satisfied customers.

Our empanellment with different departments and organisations:

  • DAK
  • CGHS NHA
  • ECHS
  • NDMC
  • DELHI JAL BOARD
  • RAILWAYS
  • NDMC
  • DGEHS
  • BSES YAMUNA / RAJDHANI POWER LTD
  • TATA POWER LTD
  • BABA SAHEB AMBEDKAR HOSPITAL
  • BJRM HOSPITAL
  • BHAGWAN MAHAVIR GOVERNMENT HOSPITAL

To know details about our empanellment with different organisations. CLICK HERE

For more details visit your nearest center today or call us now!